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EC number: 215-607-8
CAS number: 1333-82-0
Prevalence of mucosal symptoms among 37
chrome platers compared to controls
* Test of significance by Fisher's exact test when the expected number
per cell <5. Otherwise the X² test with Yate's correction was used.
Prevalence of cutaneous signs among 37
chrome platers compared to controls
* Test of significance by Fisher's exact
test when the expected number per cell <5. Otherwise the X² test with
Yate's correction was used.
of cutaneous lesions by anatomical site among 37 chrome platers
study was conducted between February and May 1984. Only factories
engaged in chrome plating for at least 5 8-h working days a week were
included in the study. On the basis of frequency of exposure to
chromium, 17 plants were selected for the study. 37 male chrome platers
and 37 male control subjects were interviewed and examined.
Muco-cutaneous symptoms experienced over the last 1 year were recorded.
They were then examined for skin disease. A patch test (carried out by
the standard method) to potassium dichromate 0.5% pet. was performed
when ulcers or dermatitis were noted.
(38%) of 37 chrome platers in 17 chrome electroplating factories
surveyed had occupational contact dermatitis, chrome ulcers, or both. 7
had chrome ulcers, 6 had contact dermatitis and 1 had both. Another 16
(43%) workers had scars suggestive of previous chrome ulcers. Mucosal
irritation was present in 57% of the workers. The most common was throat
irritation (49%) followed by nasal irritation (41%). Mucosal irritation
was more common in hard chrome platers, while skin ulcers and dermatitis
were more common in bright chrome platers. Nasal septum perforation was
seen in 1 worker. Skin ulceration appeared to be a more specific sign
for occupational dermatosis in chrome platers than dermatitis when the
prevalence rates were compared to controls. Of the 7 workers with chrome
ulcers, only 1 was allergic to chromate. Of the 6 workers with
dermatitis, 2 were allergic to chromate. The worker with ulceration and
dermatitis was negative to chromate and nickel. Irritant factors are
therefore important in the aetiology of contact dermatitis in these
mucosal symptoms in chrome platers included throat and nasal irritation,
rhinorrhoea, nose bleed and eye irritation; cutaneous signs consisted of
skin ulcer, scar of ulcer, eczema and nasal septum perforation.
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