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EC number: 227-873-2
CAS number: 6018-92-4
Most sensitive long term toxicity data for 3 different amphibians are summarised in the EU-RAR (2008). According to these data, the effect concentrations for Trinickel dicitrate were calculated:Xenopus laevis: EC10 (4d) = 0.266 mg Trinickel dicitrate/L (malformation)Gastrophryne carolensis: EC10 (7d) = 0.567 mg Trinickel dicitrate/L (malformation)Bufo terrestris: NOEC (7d) = 2.014 mg Trinickel dicitrate/L (growth)
Accepted data on chronic single-species toxicity tests resulting in high
quality NOEC/L(E)C10 values (expressed as Ni) for amphibians (n = 17)
are summarised in Table 3.2.1-7 of the EU-RAR, 2008 .
Chronic data for 3 different amphibians were extracted and used in the
effects assessment. The NOEC/L(E)C10 values for the amphibians range
from 84.5 μg Ni/L (0.266 mg Trinickel dicitrate/L) to 13,147 μg Ni/L
(41.373 mg Trinickel dicitrate/L) for Xenopus laevis. The data for
Xenopus laevis were shown in detail in the key study record in chap
6.1.8, further results for the other amphibians were only shown in the
attached document of the mentioned key study record.
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