Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 227-873-2 | CAS number: 6018-92-4
Toxicity to other aquatic organisms
Administrative data
Link to relevant study record(s)
Description of key information
Most sensitive long term toxicity data for 3 different amphibians are summarised in the EU-RAR (2008). According to these data, the effect concentrations for Trinickel dicitrate were calculated:
Xenopus laevis: EC10 (4d) = 0.266 mg Trinickel dicitrate/L (malformation)
Gastrophryne carolensis: EC10 (7d) = 0.567 mg Trinickel dicitrate/L (malformation)
Bufo terrestris: NOEC (7d) = 2.014 mg Trinickel dicitrate/L (growth)
Additional information
Accepted data on chronic single-species toxicity tests resulting in high quality NOEC/L(E)C10 values (expressed as Ni) for amphibians (n = 17) are summarised in Table 3.2.1-7 of the EU-RAR, 2008 .
Chronic data for 3 different amphibians were extracted and used in the effects assessment. The NOEC/L(E)C10 values for the amphibians range from 84.5 μg Ni/L (0.266 mg Trinickel dicitrate/L) to 13,147 μg Ni/L (41.373 mg Trinickel dicitrate/L) for Xenopus laevis. The data for Xenopus laevis were shown in detail in the key study record in chap 6.1.8, further results for the other amphibians were only shown in the attached document of the mentioned key study record.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
