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EC number: 227-873-2
CAS number: 6018-92-4
BCF (calculated using all available data) = 1613 ± 8411 (n = 52)BCF (calculated with exception of outlier data) = 157 ± 135 (n = 49)BCF (calculated over a limited range of exposure concentrations, 5-50 µg/L) = 106 ± 53 (n = 27)
An example for the uptake of nickel in fish is given in the key study
record, which described the uptake in different organs of Cyprinus
carpio at lethal and sublethal concentrations. The values were part of a
general examination of the BCF for Nickel, given by McGeer et al. (2003).
McGeer et al. had reviewed literature data to evaluate the relationship
between chronic exposure and metal accumulation in aquatic biota
including different species of algae, insects, arthropods, gastropods,
mussels and fish. They analyzed the data and calculated the mean BCF
with standard deviation (SD) using all available data, generating a BCF
of 1613 ± 8411 for nickel. To illustrate the effect of outliers, the
mean BCF was also recalculated after removal of extremely high or low
data points (greater or less than 3 SD from the mean as well as by
visual assessment) resulting in a BCF of 157 ± 135. The mean BCF was
calculated over a narrow exposure range to bracket the chronic
water-quality guidelines and criteria (just below and above the water
quality guideline value) and to encompass concentrations where chronic
toxicity might be expected to occur. This range included only data of an
exposure concentration of 5 - 50 µg/L yielding a BCF of 106 ± 53.
In general the data showed an overall trend of increased body
concentrations as exposure concentrations increased. Both overall and
within each of the individual species groups (algae, insects,
arthropods, gastropods, mussels and fish), there was a significant slope
associated with the accumulation versus exposure relationship. These
slopes were less than unity and therefore BCF was inversely correlated
with exposure. The negative relationship between Ni BCF and Ni exposure
concentration was significant in all cases and therefore the BCF cannot
be considered as an inherent property of Ni.
Furthermore the authors stated, that there was no evidence from
literature data that Nickel biomagnifies in aquatic food webs.
McGeer J.C. et al. (2003). Inverse relationship between bioconcentration
factor and exposure concentration for metals: Implications for hazard
assessment of metals in the aquatic environment. Environmetal Toxicology
and Chemistry 22(5): 1017 -1037.
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