Registration Dossier
Registration Dossier
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EC number: 268-130-2 | CAS number: 68003-46-3
Dissociation constant
Administrative data
Link to relevant study record(s)
- Endpoint:
- dissociation constant
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- key study
- Study period:
- 11 Dec 2015
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
- Principles of method if other than guideline:
- Calculated
- GLP compliance:
- no
- Dissociating properties:
- yes
- No.:
- #1
- pKa:
- 3.3
- Remarks on result:
- other: Ammonium lauroyl sarcosinate
- No.:
- #2
- pKa:
- 4.9
- Remarks on result:
- other: Ammonium laurate
Reference
Results
Since the test item was a mixture, overlapping dissociation constants would be present. For this reason, estimation of the dissociation constants was made by relevant computer-based software, and the individual results are summarized below. From these results, it can be determined that the substance would be ionised at environmentally relevant pH values. The test item is also a salt.
| Constituent Name | pKa Value |
| Ammonium lauroyl sarcosinate | 3.3 + 0.4 |
| Ammonium laurate | 4.9 + 0.4 |
Description of key information
Ammonium lauroyl sarcosinate has pKa of 3.3 (QSAR, ACD I-Lab 2.0).
Ammonium laurate has pKa of 4.9 (QSAR, ACD I-Lab 2.0).
Key value for chemical safety assessment
Additional information
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