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EC number: 203-812-5
CAS number: 110-88-3
DNA incubated with MMS exhibited an apparently smaller
increase in relative absorbance at 259 nm with a gradual increase of
temperature than native DNA. The MMS-induced decrease in an absorbance
gain was concentration dependent. Denaturation of DNA incubated with TOX
without metabolic activation ran similarly to that of control DNA and no
difference in hyperchromicity was observed. The melting of DNA incubated
with TOX in the presence of S9-mix is characterized by a considerably
lowered hyperchromicity as compared to negative control.
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