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EC number: 203-812-5
CAS number: 110-88-3
Skin irritation findings during induction:
After intradermal induction, distinct erythema and edema
were observed at the injection sites of both control and test animals,
at which only Freund's adjuvant/aqua dest. (1:1) was applied. Injection
of test substance preparation in aqua dest caused distinct erythema in
the test animals. The application areas which were injected with test
substance preparation in Freund's adjuvant/aqua dest. (1:1) exhibited
distinct erythema and edema. The control animals injected with aqua
dest. (vehicle) did not show any skin reactions.
Result of the maximization test:
No skin reactions could be observed in the control and
treated groups after both, the first and the second challenge.
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