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EC number: 203-812-5
CAS number: 110-88-3
With high probability 1,3,5-trioxane has no chronic effects to fish.
No data on chronic toxicity to fish are available. However, in Annex IX
of Regulation (EC) No 1907/2006, it is laid down that long-term toxicity
to fish shall be proposed by the registrant if the chemical safety
assessment indicates the need to investigate further the effects on
fish. According to Annex I of this regulation, the chemical safety
assessment triggers further action when the substance or the preparation
meets the criteria for classification as dangerous according to
Directive 67/548/EEC or Directive 1999/45/EC or is assessed to be a PBT
or vPvB. The hazard assessment of 1,3,5 trioxane reveals neither a need
to classify the substance as dangerous to the environment, nor is it a
PBT or vPvB substance, nor are there any further indications that the
substance may be hazardous to the environment. Therefore, and for
reasons of animal welfare, a long-term toxicity test in fish is not
provided. Moreover, since trioxane shows an unspecific mode of action a
EpiWin v4.00 EcoSAR v1.00 calculation was conducted to estimate the
chronic toxicity to fish. The result of this calculation showed no
chronic toxicity to fish (ChV > 1000 mg/L).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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