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EC number: 700-684-7
CAS number: 80793-17-5
An acute dermal irritation GLP study
according to OECD guideline 404 was conducted in 3 male New Zealand
White rabbits in order to evaluate the irritation and corrosion effects
of AC-6000 on the skin. In this study 0.5 mL of the test substance was
applied to the clipped skin of rabbits for 4 hours using a
semi-occlusive dressing. Skin reactions were assessed 1, 24, 48 and 72
hours after exposure. No skin irritation was caused by 4 hours exposure
to AC-6000. The mean (24, 48 and 72 hours) scores for erythema and edema
were both 0. Based on these results AC-6000 can be regarded as not
irritating to skin.
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