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Short-term toxicity to fish

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Description of key information

LC50 (96 h) Zebra fish > 1000 mg/l

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
1 000 mg/L

Additional information

Acute toxicity for Zebra fish was evaluated in the 96 hours screening test, according to the OECD guideline 203. Two concentrations were administrated at 562 and 1000 mg/l with no effect (Ciba - Geigy Ltd., 1992).

The study result is supported by other studies performed between 1973 and 1999 on Zebra fish at 96h for which only a summary is available indicating LC50 all greater than 1000 mg/l.

Furthermore, a prolonged semistatic assay over 14 days was conducted with Brachydanio rerio. Endpoints were mortality, signs of intoxication, length and weight. The nominal concentrations were 100, 316 and 1000 mg/l. There was no mortality and no difference in body weight at nominal concentrations of 100 and 316 mg/l. Only at 316 mg/l one fish showed slackening in movement (Bayer AG., 1992).

In conclusion, no fish acute toxicity is expected for the substance