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EC number: 700-960-7
CAS number: 68512-30-1
No biologically relevant increases
in revertant colony numbers were observed in the four tester strains, TA
1535, TA 1537, TA 98 and TA 102, following treatment with Novares LA
300, either in the presence or in the absence of metabolic activation.
An unremarkable dose-related
increase in the mutation rate was found in tester strain TA 100 under
metabolic activation: a maximum mutation factor of 2.8 was reached at a
dose of 4000 µg/plate. The mutagenic doses were cytotoxic as well.
All reference mutagens induced
distinct increases of revertant colonies indicating the validity of the
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