Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Bioaccumulation: aquatic/sediments:

Using BCFBAF Program (v3.00) model of EPI suite (2018) the estimated bioconcentration factor (BCF) for test chemical is 162.2 L/kg wet-wt at 25 deg. c which does not exceed the bioconcentration threshold of 2000. Therefore it is concluded that test chemical  is nonbioaccumulative in food chain.

Additional information

Bioaccumulation: aquatic/sediments:

Predicted data study for target chemical and experimental studies for its structurally similar read across chemicals have been reviewed for bioccumulation endpoint and their results are summarized below

In first study using BCFBAF Program (v3.00) model of EPI suite (2018) the estimated bioconcentration factor (BCF) for test chemical was determined to be 162.2 L/kg wet-wt at 25 deg. c which does not exceed the bioconcentration threshold of 2000.

To support above prediction experimental study was reviewed from authoritative database in this study the bioaccumulation study was conducted for estimating the BCF (bioaccumulation factor) value of test chemical. The bioaccumulation factor (BCF) value was calculated using a log Kow of 1.9 and a regression derived equation.

The estimated BCF (bioaccumulation factor) value of test chemical was determined to be 8.0 dimensionless.

Last study was also reviewed from authoritative database in this study the bioaccumulation study in aquatic organisms was conducted for estimating the BCF (bioaccumulation factor) value of test chemical. The bioaccumulation factor (BCF) value was calculated using a log Kow of 3.15 and a regression-derived equation. The estimated BCF (bioaccumulation factor) value of test chemical was determined to be 3 dimensionless.

The BCF values of all above mentioned studies does not exceed the bioconcentration threshold of 2000, indicating that the test chemical is considered to be non-bioaccumulative in aquatic organisms.