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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Reference
Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Justification for type of information:
Data is from computational model developed by USEPA
Qualifier:
according to
Guideline:
other: Modeling database
Principles of method if other than guideline:
Effect of test chemical was predicted by ECOSAR v1.11
GLP compliance:
no
Analytical monitoring:
no
Vehicle:
no
Test organisms (species):
Daphnia magna
Details on test organisms:
Common name WaterFlea
Test type:
flow-through
Water media type:
freshwater
Total exposure duration:
21 d
Reference substance (positive control):
no
Key result
Duration:
21 d
Dose descriptor:
NOEC
Effect conc.:
2.021 mg/L
Nominal / measured:
estimated
Conc. based on:
test mat.
Basis for effect:
reproduction
Validity criteria fulfilled:
no
Conclusions:
The NOEC value of the test chemical was predicted as 2.021 mg/L
Executive summary:

The effect of the test chemical on the daphnia magna was studied for the period of 21 days. baseed on the ECOSAR prediction tool version 1.11 the NOEC value of the test chemical was predicted as 2.021 mg/L. Based on the NOEC value, chemical consider to be nontoxic and not classified as per the CLP classification criteria.

Description of key information

The effect of the test chemical on the daphnia magna was studied for the period of 21 days. baseed on the ECOSAR prediction tool version 1.11 the NOEC value of the test chemical was predicted as 2.021 mg/L. As, chemical is readily biodegradable it cannot be classified as per new CLP classification criteria.

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater invertebrates:
2.021 mg/L

Additional information

The effect of the test chemical on the daphnia magna was studied for the period of 21 days. baseed on the ECOSAR prediction tool version 1.11 the NOEC value of the test chemical was predicted as 2.021 mg/L. As, chemical is readily biodegradable it cannot be classified as per new CLP classification criteria.