Registration Dossier

Ecotoxicological information

Long-term toxicity to fish

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
adult fish: sub(lethal) effects
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
accepted calculation method
Justification for type of information:
Data is from computational model developed by USEPA
Qualifier:
according to
Guideline:
other: Modeling database
Principles of method if other than guideline:
Long term toxicity of test chemical were determined on the basis of predicted mortality of fish.
GLP compliance:
no
Analytical monitoring:
no
Vehicle:
no
Test organisms (species):
other: Fish
Test type:
flow-through
Water media type:
freshwater
Total exposure duration:
28 d
Reference substance (positive control):
no
Key result
Duration:
28 d
Dose descriptor:
NOEC
Effect conc.:
0.568 mg/L
Nominal / measured:
estimated
Conc. based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other: Other details not known
Validity criteria fulfilled:
not specified
Conclusions:
On the basis of no effects observed in fish, freshwater system, the NOEC value for the substance is estimated to be 0.568 mg/l for aquatic fish for 28 days of exposure duration.
Executive summary:

Long Term Toxicity to Fish

Based on the prediction done using ECOSAR version 1.11, the long term toxicity on fish was predicted for test substance . On the basis of effects observed in a flow through freshwater system, the NOEC value for the test substance is estimated to be 0.568 mg/l for aquatic vertebrate for 28 days of exposure,

Based on the obtained value the test chemical can be classified into aquatic chronic 3

Description of key information

Based on the prediction done using ECOSAR version 1.1, the long term toxicity on fish was predicted for test substance . On the basis of effects observed in a flow through freshwater system, the NOEC value for the test substance is estimated to be 0.568 mg/l for aquatic vertebrate for 28 days of exposure,

Based on the obtained value the test chemical can be classified into aquatic chronic 3

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater fish:
0.568 mg/L

Additional information

Long Term Toxicity to Fish

Based on the prediction done using ECOSAR version 1.11, the long term toxicity on fish was predicted for test substance . On the basis of effects observed in a flow through freshwater system, the NOEC value for the test substance is estimated to be 0.568 mg/l for aquatic vertebrate for 28 days of exposure,

Based on the obtained value the test chemical can be classified into aquatic chronic 3