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EC number: 202-049-5
CAS number: 91-20-3
Table 1: Macroscopic pathology
incidence summary – terminal kill (from Report, Table 8)
Only organs showing any anomalies are included)
Animals on study
Table 2: Microscopic pathology
incidence summary (from Report, Table 10)
(Note: Only organs showing any
anomalies are included)
No abnormalities detected
Luminal dilatation (total)
Cystic corpus luteum
Tubular atrophy (total)
Ten male and ten female
CRL:CD®(SD)BR Sprague-Dawley rats were exposed nose-only to 0, 2, 10,
and 60 (58 measured) ppm for six hours a day for five days a week for 13
consecutive weeks. Detailed macroscopic examinations of each rat was
performed and organ weights of ovaries, prostate, testes with
epididymides were controlled. Microscopic examination of testes plus
epididymides, prostate, seminal vesicles, uterus (corpus plus cervix),
oviduct and ovaries was performed. No treatment-related effects or
alteration in any reproductive organ was found (testes, epididymides,
uterus, cervix, ovaries, and oviducts) after exposure to naphthalene by
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