Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

There is no information available on skin sensitisation in humans or respiratory sensitisation in humans or animals. In animal skin sensitisation studies, negative results were obtained in both a maximisation and a Buehler study, although both had limitations in either conduct or reporting. However, in view of the use of naphthalene for many years in occupational and consumer settings, the absence of reports that naphthalene produces skin or respiratory sensitisation suggests that these endpoints are not of concern for human health and no further information is required.


Migrated from Short description of key information:
In animal skin sensitisation studies, negative results were obtained in both a maximisation and a Buehler study.

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

There is no information available on respiratory sensitisation in humans or animals. However, in view of the use of naphthalene for many years in occupational and consumer settings, the absence of reports that naphthalene produces skin or respiratory sensitisation suggests that these endpoints are not of concern for human health and no further information is required.


Migrated from Short description of key information:
In view of the use of naphthalene for many years in occupational and consumer settings, the absence of reports that naphthalene produces respiratory sensitisation suggests that these endpoints are not of concern for human health and no further information is required.

Justification for classification or non-classification

In view of the use of naphthalene for many years in occupational and consumer settings, the absence of reports that naphthalene produces skin or respiratory sensitisation suggests that these endpoints are not of concern for human health and no classification is required.