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EC number: 202-216-2
CAS number: 93-08-3
The in-vitro eye irritation study was
conducted to determine the ocular irritation potential of test article
was determined according to the OECD 492 test guideline for this study.
The MatTek EpiOcular™ model was used to assess the potential ocular
irritation of the test articles by determining the viability of the
tissues following exposure to the test article via MTT. Tissues were
exposed to solid test articles and control for approx.6 hours, followed
by a 25 minute post-soak and approximately 18 hours recovery after the
post-soak. The viability of each tissue was determined by MTT assay. The
MTT data show the assay quality controls were met, passing the
acceptance criteria. The mean % tissue viability of test substance was
determined to be 9.3%. Hence, under the experimental test conditions it
was concluded that test substance was considered to be irritating to the
human eyes and can thus be classified as ‘’Irritating to eyes in
Category 2” as per CLP Regulation.
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