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EC number: 905-806-4
CAS number: -
test substance is covered by the category approach of methylenediphenyl
diisocyanates (MDI). Hence, data of the category substances can be used
to cover this endpoint. The read-across category justification document
is attached in IUCLID section 13. It is important to note that the MDI
category approach for read-across of environmental and human hazards
between the MDI substances belonging to the MDI category is work in
progress under REACH. Therefore the document should be considered a draft
The main removal mechanism of MDI in the environment is hydrolysis. MDI
reacts quickly with water to form predominantly solid, insoluble
polyureas. Under conditions typical of many types of environmental
contact, i. e. with relatively poor dispersion of the denser isocyanate,
the interfacial reaction leads to the formation of a solid crust
encasing partially or unreacted material. This crust restricts ingress
of water and egress of amine, and hence slows and modifies hydrolysis.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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