Registration Dossier

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

The test substance is covered by the category approach of methylenediphenyl diisocyanates (MDI). Hence, data of the category substances can be used to cover this endpoint. The read-across category justification document is attached in IUCLID section 13. It is important to note that the MDI category approach for read-across of environmental and human hazards between the MDI substances belonging to the MDI category is work in progress under REACH. Therefore the document should be considered a draft

No terrestrial toxicity tests were performed with the test substance, but some limited acute terrestrial toxicity data is available for an analogue covered by the category approach of the methylenediphenyl diisocyanates (MDI).

Two separate short-term toxicity studies (van der Hoeven et al, 1992) are available with terrestrial organisms for polymeric MDI. For the earthworm Eisenia fetida, tested according to OECD 207, a 14d-EC50 of 1000 mg/kg soil (d.w.) was obtained. For the plants Avena sativa and Lactuca sativa, tested according to OECD 208, 14d-EC50 of 1000 mg/kg soil (d.w.) values were obtained. The values may be considered for the derivation of a PNEC soil.