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Toxicological information

Acute Toxicity: dermal

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Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
The information does not come from a test report, and only minimum fields required can be filled in.

Data source

Referenceopen allclose all

Reference Type:
other: database
Title:
Triethyl citrate, CAS# 77-93-0, RTECS# GE8050000
Author:
Canadian Centre for Occupational Health & Safety (CCOHS)
Year:
2010
Bibliographic source:
Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963- 81,p. 389; cited in RTECS database (Registry of Toxic Effects of Chemical Substances, 2010)
Reference Type:
other: database
Title:
GESTIS Substance Database: Triethylcitrat
Author:
Institut für Arbeitsschutz der Deutschen Gesetzlichen Unfallversicherung (IFA, Institute for Occupational Safety and Health of the German Social Accident Insurance)
Year:
2010
Bibliographic source:
www.dguv.de/ifa/gestis-database

Materials and methods

Test guideline
Qualifier:
no guideline required
Principles of method if other than guideline:
Handbook data
GLP compliance:
not specified
Remarks:
Handbook data, with no information on GLP status
Test type:
other: no data

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rabbit
Strain:
not specified
Sex:
not specified

Administration / exposure

Type of coverage:
not specified
Vehicle:
not specified
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 5 000 mg/kg bw
Based on:
not specified

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: other: EU-GHS
Conclusions:
LD50 (rabbit) >5000 mg/kg
Executive summary:

In the Registry of Toxic Effects of Chemical Substances (RTECS) database and the GESTIS substance database a LD50 (rabbit) of 5000 mg/kg bw is reported for triethyl citrate. No further details are available.