Registration Dossier
Registration Dossier
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EC number: 201-070-7 | CAS number: 77-93-0
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- The information does not come from a test report, and only minimum fields required can be filled in.
Data source
Reference
- Reference Type:
- other: database
- Title:
- Triethyl citrate, CAS# 77-93-0, RTECS# GE8050000
- Author:
- Canadian Centre for Occupational Health & Safety (CCOHS)
- Year:
- 2 010
- Bibliographic source:
- "Industrial Hygiene and Toxicology," 2nd ed., Patty, F.A., ed., New York, John Wiley & Sons, Inc., 1958-63,p. 1892; cited in RTECS database (Registry of Toxic Effects of Chemical Substances, 2010)
Materials and methods
Test guideline
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- peer-reviewed database
- GLP compliance:
- not specified
- Remarks:
- Peer-reviewed database, with no information on GLP status
- Test type:
- other: no data
Test material
- Reference substance name:
- Triethyl citrate
- EC Number:
- 201-070-7
- EC Name:
- Triethyl citrate
- Cas Number:
- 77-93-0
- Molecular formula:
- C12H20O7
- IUPAC Name:
- triethyl citrate
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- inhalation
- Type of inhalation exposure:
- not specified
- Vehicle:
- not specified
- Analytical verification of test atmosphere concentrations:
- not specified
- Duration of exposure:
- 6 h
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LC50
- Effect level:
- 1 300 ppm
- Based on:
- not specified
- Exp. duration:
- 6 h
- Other findings:
- Lungs, thorax or respiration:
- acute pulmonary oedema
- pleural effusion
- dyspnoea
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: other: EU-GHS
- Conclusions:
- LC50 (rat) = 1300 ppm/6h
- Executive summary:
In the Registry of Toxic Effects of Chemical Substances (RTECS) database a LC50 (rat, inhalation) of 1300 ppm/6h is reported for triethyl citrate. No further details are available.
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