Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 208-031-3 | CAS number: 506-30-9
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Final Report on the Safety Assessment of Oleic Acid, Lauric Acid, Palmitic Acid, Myristic Acid, and Stearic Acid
- Year:
- 1 987
- Bibliographic source:
- Journal of the American College of Toxicology.(Mary Ann Liebert,Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued.Volume(issue)/page/year: 6(3),321,1987
- Reference Type:
- review article or handbook
- Title:
- RTECS NUMBER : WI2800000
- Author:
- RTECS Database
- Year:
- 2 012
- Bibliographic source:
- RTECS (Registry of Toxic Effects of Chemical Substances);Journal of the American College of Toxicology.(Mary Ann Liebert,Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued.Volume(issue)/page/year: 6(3),321,1987
Materials and methods
- Principles of method if other than guideline:
- The acute toxicity study was conducted to evaluate the toxic effects of administration of Stearic acid to rat by the oral route.
- GLP compliance:
- not specified
- Test type:
- standard acute method
Test material
- Reference substance name:
- Stearic acid
- EC Number:
- 200-313-4
- EC Name:
- Stearic acid
- Cas Number:
- 57-11-4
- Molecular formula:
- C18H36O2
- IUPAC Name:
- stearic acid
- Details on test material:
- - Name of test material (as cited in study report):Stearic acid
- Molecular formula :C18H36O2
- Substance type:Organic
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LDLo
- Effect level:
- 4 640 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: Non toxic to rats.
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The Lowest published lethal dose (LDLo) of Stearic acid in rat was found to be 4640 mg/kg of body weight.Toxic effects was not observed. Thus by considering the CLP criteria for acute toxicity rating for the chemicals, it infers that Stearic acid does not exhibit acute toxicity via the oral route i.e it is acutely non toxic to animals within the dose level mentioned in the study.
- Executive summary:
The acute toxicity study was conducted to evaluate the toxic effects of administration of Stearic acid to rat by the oral route. The Lowest published lethal dose (LDLo) of Stearic acid in rat was found to be 4640 mg/kg of body weight.Toxic effects was not observed. Thus by considering the CLP criteria for acute toxicity rating for the chemicals, it infers that Stearic acid does not exhibit acute toxicity via the oral route i.e it is acutely non toxic to animals within the dose level mentioned in the study.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
