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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

The lethal concentration (LC50) value of Eicosanoic acid in fish [Carassius auratus] in a 96 hr study on the basis of mortality effect was estimated to be 4.67 mg/L. Based on this LC50 value,the substance may qualify for the aquatic classification.But after compairing with other CLP criteria for BCF and biodegradation it is concluded that Eicosanoic acid does not exhibit short term toxicity to fish (Carassius auratus) i.e. it is non hazardous to the aquatic environment.

Key value for chemical safety assessment

LC50 for freshwater fish:
4.67 mg/L

Additional information

Based on weight of evidence approach the no.of studies were reviewed for short-term toxicity to fish from reliable sources having Klimish rating 2 and 4.

The summary of the results are presented below

Sr. No

Endpoint

Value

Duration

Basis of effect

Species

Sources

1.

LC50

4.67 mg/L

 96 hr.

Mortality

Carassius auratus

Predicted data from QSAR for CAS : 506-30-9

2.

LC50

12 mg/L

96 hr.

Mortality

Oncorhynchus kisutch

Experimental data for RA CAS : 57-11-4

3.

LC50

>5 mg/L

96 hr.

Mortality

Oryzias latipes

Experimental data from study report for RA CAS : 112-85-6

4.

LC50

40 mg/L

48 hr

Mortality

Oryzias latipes

Experimental data for RA CAS : 8002-13-9

 

Based on the studies summarized in the above table for the target substance Eicosanoic acid and the read across substance,the endpoint value was found to vary between lethal concentration (LC50) = 4.67 mg/L to 40 mg/L in a 48 hrs. to 96 hrs.study on the basis of mortality effect. Based on the LC50 values, the substance may qualify for the aquatic classification.But after compairing with other CLP criteria for BCF and biodegradation it is concluded that Eicosanoic acid does not exhibit short term toxicity to fish (Carassius auratus, Oncorhynchus kisutch and Oryzias latipes) i.e. it is non hazardous to the aquatic environment.