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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Description of key information

Based on the results for the two major constituents the NOEC for the substance is estimated to be 3 mg/L

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater invertebrates:
3 mg/L

Additional information

To determine the chronic toxicity of 2,2',2"-nitrilotriethanol to aquatic invertebrates, a non-GLP study following an internal method of the German Federal Environmental Agency was performed using a semi-static procedure (Kuehn et al./UBA 1989). The calculated NOEC value for Daphnia magna after an exposure period of 21 days in this study was 16 mg/l.

For DEA there is one valid BASF GLP semi-static study conducted 1992 according to the draft EEC guideline XI/681/86 "Prolonged toxicity study withDaphnia magna: Effects on reproduction" available. The NOEC after 21 days of exposure based on reproduction was determined to be 0.78 mg/L.

Since DEA is present in the substance at a maximum amount of 25% the NOEC for the substance is estimated to be 0.78/0.25= 3.12 mg/L