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EC number: 905-898-6
CAS number: -
In total 85098
patients were tested with TEA. Of these 323 (0.35%) patients were tested
positively to TEA. The reaction index was calculated to -0.49. Most of
the reactions were weak positive reactions resulting in a high positive
reactions to TEA in all patients tested from 1992 -2007
DEA (n = 85098)
Regarding the MOAHLFA
index, there were only minor differences between patients with positive
and those without positive reactions to the diethanolamine.
Frequency of characteristics (%) in TEA-positive (cases) vs. non
positive (controls) patients
Age ≥ 40 years
Reactions to DEA
and occupational exposure (metal workers)
If the prevalence of
positive reactions in probably water-based metalworking fluids-exposed
current male cutting workers is compared with the prevalence in all male
patients not working in the metal industry at present, about five to
sevenfold higher portion of positive reactions is recorded for MEA and DEA,
respectively. For TEA, the prevalence is increased about three times
with only 10 patients showing a (weakly) positive reaction.
Reactions to DEA
associated with other (non-)occupational applications
In accordance with the
unremarkable proportion of occupation-related cases, there were no
distinctly different patterns of occupations inTEA-positive versus
non-positive patients. There was no difference between the TEA-positive and
theTEA non-positive subgroup of patients with regard to the frequencies
of suspected causative exposures, such as a similar proportion of about 60%
regarding presumable causation of contact dermatitis by cosmetics and
topical therapeutics. The association between sporadic sensitization to
TEA from exposure to cosmetics or topical
reflected by the high proportion of concomitant reactions to some
substances, which are mainly used in these fields, that is fragrance mix
(and Myroxylon pereirae), lanolin alcohol and cetearyl alcohol, and
parabens. However, concomitant reactions indicating possibly
irritant reactions have also been documented, for example for octyl
gallate, phenyl mercuric acetate, propylene glycol, and cocamidopropyl
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