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EC number: 451-620-7
CAS number: 352230-22-9
Table: Mortality and observed
*number of dead fish plus number
of fish with visible abnormalities
Table: Concentrations of the test
item in test medium
100 mg/l WAF loading rate
% of nominal
*LOD (Limit of Detection) = 0.0001
96-hour LL50 >100 mg/L
(nominal, WAF loading rate) (highest concentration tested); mortality of Danio
A 96-hour LL50 value of
>100 mg/L (nominal, WAF loading rate) (highest concentration tested) has
been determined for the effects of the submission substance (CAS
352230-22-9) on mortality of Danio rerio, in accordance with OECD
Guideline 203 (Fish, Acute Toxicity Test).
The study reports an analytically
determined test substance concentration of <0.1 µg/L (<LOD, mean
measured). This value reflects the low water solubility of the test
substance, but losses may also have occurred as a result of filtering of
the test solution prior to addition of test organisms, and the potential
for adsorption of the test substance onto the filter matrix.
Each constituent of the test
substance has a slow hydrolysis half-life at pH 7 (predicted to be >200
to >630 hours). However, the hydrolysis rate greatly increases with
higher pH; 2 to 5.3 hours at pH 9. As this test was conducted at pH 8.1
to 8.3, hydrolysis will have occurred in the timescale of the test. In
view of the test media preparation method and static exposure regime it
is likely that the test organisms were exposed to a mixture of the
parent substance and the hydrolysis products of each constituent of the
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