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EC number: 451-620-7
CAS number: 352230-22-9
Table: Algal cell densities during
the test period of 72 hours
72-hour ErL50: >100
mg/l; NOELR: >=100 mg/L (nominal, WAF loading rate) (highest
concentration tested); effects of the submission substance (CAS
352230-22-9) on growth rate of Scenedesmus subspicatus.
A 72-hour ErL50 value
of >100 mg/L and a NOELR value of ≥100 mg/L (nominal, WAF loading rate)
(highest concentration tested) have been determined for the effects of
the submission substance (CAS 352230-22-9) on growth rate of Scenedesmus
subspicatus, in accordance with OECD Guideline 201 (Alga, Growth
The study reports an analytically
determined test substance concentration of 1.4 µg/L (mean measured).
This value reflects the low water solubility of the test substance, but
losses may also have occurred as a result of filtering of the test
solution prior to addition of test organisms, and the potential for
adsorption of the test substance onto the filter matrix.
Each constituent of the test
substance has a slow hydrolysis half-life at pH 7 (predicted to be >200
to >630 hours). However, the hydrolysis rate greatly increases with
higher pH; 2 to 5.3 hours at pH 9. This test was conducted at pH 8.0 -
8.9. Hydrolysis is likely to have occurred in the timescale of the test.
In view of the test media preparation method and the static exposure
regime it is likely that the test organisms were exposed to a mixture of
the parent substance and the hydrolysis products of each constituent of
the tested substance.
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