Registration Dossier

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

The substance is acutely harmful to aquatic invertebrates.

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
27 mg/L

Additional information

Experimental data on the acute toxicity of 1,2-propanediamine (CAS 78-90-0) to aquatic invertebrates are not available. However, data are available for all the source substance 1,3 -propanediamine (CAS 109 -76 -2). The effects of the source substance to Daphnia magna was studied according to EU method C.2 which is equivalent to OECD 202. The test item concentrations were not analytically verified. However, it is assumed that the test concentrations remained stable over the exposure period based on a sufficiently high water solubility, a low potential to evaporate into air (Henry’s Law constant < 1 Pa*mol/cm³) and a low potential for adsorption (log Kow and log Koc < 3). The 48-h EC50 was determined to be 27.0 mg/L (BASF AG, 1989; report no. 1/0498/2/89 -0498/89). The highest test concentration (500 mg/L) was also studied after pH-adjustment, but showed no significant reduction of toxicity. Nevertheless, it cannot be ruled out that the observed toxicity of the test substance is at least partly due to the pH-shift in the test solutions as the initial pH of the test concentrations above 15 mg/L had a pH > 9.0. This pH is the upper acceptable limit according to the OECD guideline 202.

Based on the experimental data for the structural analogue 1,3-propanediamine (CAS 109-76-2), it can be concluded that 1,2-propanediamine is acutely harmful to aquatic invertebrates.