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Toxicity to microorganisms

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Description of key information

NOEC (14 d): ≥ 18.1 mg/L for acitvated sludge microorganisms (OECD 301B)

Key value for chemical safety assessment

Additional information

The toxicity of 1,3-butylene diacetate (CAS 1117-31-3) to microorganisms was investigated in a biodegradation study according to OECD 301B under GLP conditions (Roulstone, 2012). An additional toxicity control containing activated sludge of a predominantly domestic sewage, reference substance (sodium benzoate) and the test substance at a concentration of 18.1 mg/L. The toxicity control attained 78% degradation after 14 d of incubation. Since more than 35% degradation was observed in the toxicity control, the substance is with high probability not toxic to aquatic microorganisms. The test item concentration in the toxicity control of 18.1 mg/L can be used as NOEC value for the toxicity to aquatic microorganisms. Thus a NOEC (14 d) of ≥ 18.1 mg/L resulted.