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EC number: 214-244-2
CAS number: 1117-31-3
Table 1. Degree of hydrolysis
Sample pH (mean of 3 samples)
Mean concentration (mg/L), n=3
Log10 Concentration (mg/L)
Degree of hydrolysis (%)
Table 2. Results of linear regression
2.67E-02 per h (7.42E-06 per sec)
25.9 h (1.08 days)
Table 3. Acetic acid concentration
The linearity of the detector response with respect to
concentration was assessed over the concentration range of 15 to 300
mg/L for both test item an acetic acid. This was satisfactory with
correlation coefficients (r) of 0.999 being obtained for each analyte.
It was observed that the concentration of acetic acid in the
sample solutions increased with time and was most likely due to
hydrolysis of the test item.
A peak in the chromatography at approximately 12.7 minutes, which
was not present in the standard solutions, was observed to increase in
magnitude over the period of the test. This was not identified or
quantified but was considered most likely to be ethylene glycol
monoacetate, a degradation product of the test item.
The rate constant and half-life at 37 °C of the test item in
simulated intestinal fluid at pH 7.5 were determined and are shown below.
Table 4. Rate constant and half-life time
Rate constant (per sec)
Estimated half-life at 37 °C
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