Registration Dossier

Administrative data

Endpoint:
relative density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
from 13 April 2018 to 09 May 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
The substance can be produced through different process routes, yielding solutions in water or organic solvent (e.g. methanol or ethylene glycol).
It was initially unclear how to register the substance (mono-constituent or multi-constituent substance) and which manufactured substance to test to fulfil the REACH data requirements. After consultation with the ECHA helpdesk, the test program was started with the manufactured substance of the Lead registrant (solvent: methanol) in which the highest amount of solvent could be removed without causing degradation of the substance. This resulted in the selection of a solution of 56-57% BTMAOH in methanol as test substance.
During the course of the test program, and in order to aid meaningful risk assessment, after consultation with ECHA and upon ECHA's recommendation, it was considered to be more appropriate to test the water-based manufactured substance. As a consequence, some testing was performed with a BTMAOH solution in methanol, and some testing was performed with a BTMAOH solution in water.

The current entry reflects a test performed with a methanol-based test solution.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report Date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
EU Method A.3 (Relative Density)
Version / remarks:
2016
Deviations:
no
Qualifier:
according to
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Version / remarks:
2012
Deviations:
no
Qualifier:
according to
Guideline:
EPA OPPTS 830.7300 (Density / Relative Density / Bulk Density)
Version / remarks:
2002
Deviations:
no
GLP compliance:
yes
Type of method:
pycnometer method

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
liquid
Details on test material:
Appearance: Clear colourless liquid
Test item storage: At room temperature
Dynamic viscosity of test material:
no data

Results and discussion

Densityopen allclose all
Key result
Type:
relative density
Density:
0.957 other: dimensionless
Temp.:
20 °C
Remarks on result:
other: D 20 /4
Key result
Type:
density
Density:
0.957 g/cm³
Temp.:
20 °C

Any other information on results incl. tables

Table: Volume of the pycnometer

 

Test 1

Test 2

Mean

Mass empty pycnometer (A)

30.4747 g

30.4748 g

30.4748 g

Mass pycnometer with water (B)

40.1106 g

40.1105 g

 

Volume of the pycnometer [cm^3]

9.6533

9.6531

9.6532

 

Table: Density of the test item

 

Test 1

Test 2

Mean

Mass pycnometer with test item (C)

39.7105 g

39.7187 g

 

Density [g/cm^3]

0.9568

0.9576

0.957

Applicant's summary and conclusion

Conclusions:
The relative density D20/4 of the substance in methanol was determined to be 0.957.
Executive summary:

The relative density was determined using the pycnometer method in a GLP study according to EC A.3, OECD 109 and OPPTS 830.7300. A solution of 56 -57% Benzyltrimethylammonium hydroxide in methanol was tested. A 10 mL volume pycnometer was used. The relative density D20/4 of the substance in methanol was determined in duplicate at 20°C obtaining a mean value of 0.957.

Based on a relative density of methanol of ca 0.8 (SciFinder data base, 25 oct 2018) it can be concluded that the relative density of BTMAOH is ≥ 0.957.