Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 946-365-8
CAS number: -
Summary of other skin sensitisation studies
data is being read across from the source study that tested
Hydrocarbons, C9, aromatics based on analogue read across.
A Hartley dermal sensitization test was
conducted on 30 guinea pigs. Following a preliminary irritation test, 15
Hartley guinea pigs were treated by intradermal injection (0.01 mL; 5.0%
(w/v) vehicle/MRD-83 -208 or with adjuvant) to induce sensitization and
then further sensitized by dermal application of 0.5 ml MRD-83 -208 a
week after the intradermal injection. Guinea pigs were challenged two
weeks later by topical application (0.5 ml 0.5% MRD-83 -208).
No indication of sensitization was noted.
Based on the scored of dermal irritation,
test substance MRD-83 -208 would not be considered a dermal sensitizer
under either EU GHS guidelines or under the EU requirements for
dangerous substances and preparations guidelines.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
På den här webbplatsen används kakor. Syftet är att optimera din upplevelse av den.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again