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Diss Factsheets
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EC number: 201-969-4 | CAS number: 90-15-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- K1 from publicly available IUCLID 2003 file, study not available to confirm K1
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 211 (Daphnia magna Reproduction Test)
- Deviations:
- no
- GLP compliance:
- yes
- Analytical monitoring:
- yes
- Test organisms (species):
- Daphnia magna
- Water media type:
- freshwater
- Key result
- Duration:
- 21 d
- Dose descriptor:
- EC50
- Effect conc.:
- > 1 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- immobilisation
- Key result
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.25 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
- Key result
- Duration:
- 21 d
- Dose descriptor:
- LOEC
- Effect conc.:
- 0.5 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
- Key result
- Duration:
- 21 d
- Dose descriptor:
- other: maximum acceptable toxicant concentration (MATC)
- Effect conc.:
- 0.38 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
- Details on results:
- After 21 days, immobilization did not exceed 40% in any exposed group.
Consistent and statistically significant effects on reproductive performance and growth were observed at the nominal concentrations of 0.5 and 1.0 mg/l. No significant effects were observed at lower concentrations. - Validity criteria fulfilled:
- yes
- Conclusions:
- 1-naphthol tested in a 21-day Daphnia magna study gave an EC 50 > 1 mg/L (immobilization), NOEC 0.25 mg/L (reproduction rate), LOEC 0.5 mg/L (reproduction rate) and MATC 0.38 mg/L (reproduction rate).
- Executive summary:
1-naphthol tested in a 21-day Daphnia magna study gave an EC 50 > 1 mg/L (immobilization), NOEC 0.25 mg/L (reproduction rate), LOEC 0.5 mg/L (reproduction rate) and MATC 0.38 mg/L (reproduction rate).
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Principles of method if other than guideline:
- calculation
- Duration:
- 21 d
- Dose descriptor:
- other: ChV
- Effect conc.:
- 0.583 mg/L
- Remarks on result:
- other: ECOSAR v1.11 calculation, Phenols class
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- The calculated (ECOSAR v1.11, Phenols class) ChV (21d) is 0.583 mg/L, in line with the experimental 21-day Daphnia magna study NOEC 0.25 mg/L (reproduction rate)
- Executive summary:
The calculated (ECOSAR v1.11, Phenols class) ChV (21d) is 0.583 mg/L, in line with the experimental 21-day Daphnia magna study NOEC 0.25 mg/L (reproduction rate)
Referenceopen allclose all
Description of key information
1-naphthol tested in a 21-day Daphnia magna study gave an EC 50 > 1 mg/L (immobilization), NOEC 0.25 mg/L (reproduction rate), LOEC 0.5 mg/L (reproduction rate) and MATC 0.38 mg/L (reproduction rate).
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.25 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.