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Physical & Chemical properties

Partition coefficient

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Endpoint:
partition coefficient
Type of information:
not specified
Remarks:
noted as computer estimated or retrieved as measured value from SRC-WSKOW for Microsoft Windows (version 1.26)
Adequacy of study:
weight of evidence
Study period:
2003
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment
Remarks:
noted as computer estimated or retrieved as measured value from SRC-WSKOW for Microsoft Windows (version 1.26)
Principles of method if other than guideline:
calculation
Type of method:
other: SRC-WSKOW for Microsoft Windows version 1.26
Partition coefficient type:
octanol-water
Type:
log Pow
Partition coefficient:
2.85
Remarks on result:
other: noted as computer estimated or retrieved as measured value from SRC-WSKOW for Microsoft Windows (version 1.26)
Remarks:
templerature and pH not noted
Conclusions:
The reported log Kow is 2.85
Executive summary:

The reported log Kow is 2.85

Endpoint:
partition coefficient
Type of information:
not specified
Remarks:
list of substance log Kow values noted as calculated or experimentally determined, unclear which
Adequacy of study:
weight of evidence
Study period:
2000
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment
Remarks:
list of substance log Kow values noted as calculated or experimentally determined, unclear which; value in line with other WoE references
Principles of method if other than guideline:
not clear if experimental or calculated
Type of method:
other: not clear if experimental or calculated
Partition coefficient type:
octanol-water
Type:
log Pow
Partition coefficient:
2.84
Remarks on result:
other: unclear if experimental or calcualtion
Remarks:
temperature and pH not noted
Conclusions:
reported log Kow of 1-naphthol is 2.84
Executive summary:

reported log Kow of 1-naphthol is 2.84

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
2008
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation
Remarks:
no purity information, noted as "analytical pure"
Qualifier:
equivalent or similar to
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Deviations:
not specified
GLP compliance:
not specified
Type of method:
flask method
Partition coefficient type:
octanol-water
Type:
log Pow
Partition coefficient:
2.836
Temp.:
25 °C
Remarks on result:
other: pH not specified
Conclusions:
Experimentally determined log Kow is 2.836 @ 25 oC
Executive summary:

Experimentally determined log Kow is 2.836 @ 25 oC

Endpoint:
partition coefficient
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
weight of evidence
Study period:
2002
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification
Principles of method if other than guideline:
determination of Abraham descriptors to enable calculation of log Kow
Type of method:
HPLC method
Remarks:
determination of Abraham descriptors to enable calculation of log Kow
Partition coefficient type:
octanol-water
Type:
log Pow
Partition coefficient:
2.84
Remarks on result:
other: calculated
Conclusions:
The calculated log Kow is 2.84
Executive summary:

The calculated log Kow is 2.84

Description of key information

Log Kow is 2.84 based on four WoE literature articles

Key value for chemical safety assessment

Log Kow (Log Pow):
2.84
at the temperature of:
25 °C

Additional information