2-bromopropane

Biodegradation in water: screening tests

Administrative data

Endpoint:

biodegradation in water: ready biodegradability

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Partial report available. Report states that the study meets all criteria for reliability, but not all information could be verified.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1995

Report date:

1995

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

EU Method C.4-E (Determination of the "Ready" Biodegradability - Closed Bottle Test)

Version / remarks:

also acc. to OECD 301 D

Deviations:

no

Test material

Test material information

Constituent 1

Reference substance name:

2-bromopropane

EC Number:

200-855-1

EC Name:

2-bromopropane

Cas Number:

75-26-3

Molecular formula:

C3H7Br

IUPAC Name:

2-bromopropane

Study design

Oxygen conditions:

aerobic

Duration of test (contact time):

28 d

Parameter followed for biodegradation estimation

Parameter followed for biodegradation estimation:

O2 consumption

Reference substance

Reference substance:

benzoic acid, sodium salt

Results and discussion

Test performance:

The criteria for test validity have been met:
The difference between the highest and lowest values of replicates obtained in the test series (Series 2) is less than 20%;
The percentage of degradation of reference substance in the series inoculum control (Series 4) is greater than 60% in 14 days;
The degradation of reference substance in the inhibition control (Series 3) exceeds 25% during the first 14 days;
the degradation of reference substance has not been inhibited by the presence of the test substance;
The loss of oxygen in blank (Series 1) (does not contain inoculum) exceeded 1.5 mg/l of dissolved oxygen after 28 days;
The residual oxygen concentration in the test flasks has always been greater than 0.5 mg/l throughout the duration of the test.

% Degradation

Parameter:

% degradation (O2 consumption)

Value:

68.6

Sampling time:

21 d

Remarks on result:

other: plateau @ 21 d

Details on results:

The substance showed no inhibitory effect vis-a-vis micro-organisms. The criteria for a valid test have been met: The difference between the
highest and lowest values of replicates obtained in the test series (Series 2) is less than 20%.

BOD5 / COD results

Results with reference substance:

The percentage of degradation of reference substance is greater than 60% in 14 days; The degradation of reference substance has not been inhibited by the presence of the test substance.

Applicant's summary and conclusion

Validity criteria fulfilled:

yes

Interpretation of results:

readily biodegradable

Conclusions:

Under the conditions of the test, the percent biodegradation of 2-bromo -Propane was 68.6% in 21 days (plateau). Ten days following the beginning of the test, it reached approximately 56% biodegradation. The substance may be considered "readily biodegradable" according to the criteria in Guideline 301 of the OECD.

Executive summary:

The biodegradability of 2 -bromopropane was conducted using procedures set forth in Annex C.4-E to Directive 92/69/EEC. This protocol is in agreement with the OECD Guideline No. 301 D adopted 17/7/92. RESULTS SYNOPSIS*:Under the conditions of the test, the percent biodegradation of 2-bromo -Propane was 68.6% in 21 days (plateau). Ten days following the beginning of the test,it has reached about 56% biodegradation. The substance may be considered "readily biodegradable" according to the criteria in Guideline 301 of the OECD. *Partial report available. Report states that the study meets all criteria for reliability, but not all information can be verified.