Registration Dossier

Physical & Chemical properties

Solubility in organic solvents / fat solubility

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
25 June 2020 to 29 June 2020
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
comparable to guideline study
Qualifier:
according to guideline
Guideline:
other: CIPAC Handbook for the Analysis of Technical and Formulated Pesticides, Book H, Method MT 181.
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: OECD Guidelines for Testing of Chemicals
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: Commission Regulation (EC) No 440/2008 (as amended)
Version / remarks:
30 May 2008
GLP compliance:
yes
Key result
Medium:
n-octanol
Solubility:
> 250 g/L
Temp.:
20 °C
Test substance stable:
not determined
Details on results:
PRELIMINARY TEST
The recorded observations for the contents of the cylinder after each addition of n-octanol are:
0.5 mL volume of n-octanol added: >203 g/L saturation concentration. The observations were of a clear, colourless, single phase liquid.
The solubility was estimated to be greater than 203 g/L at 20.0 ± 0.5 °C and definitive testing was continued using the method MT 181.

DEFINITIVE TEST
The recorded observations for the contents of the cylinder after each addition of n-octanol are: 2 mL total volume of n-octanol added: Saturation concentration of Sample 1 was > 253 g/L. Saturation concentration of Sample 2 was > 250 g/L. The observations were of a clear colourless, single phase liquid.
The solubility was estimated to be greater than 250 g/L at 20.0 ± 0.5 °C.
Conclusions:
Under the conditions of the study the solubility of the test material in n-octanol was determined to be greater than 250 g/L of solution at 20.0 ± 0.5 °C.
Executive summary:

The solubility in n-octanol of the test material was determined by a visual evaluation method, designed to be compatible with the CIPAC Handbook for the Analysis of Technical and Formulated Pesticides, Book H, Method MT 181. 

Under the conditions of the study the solubility of the test material in n-octanol was determined to be greater than 250 g/L of solution at 20.0 ± 0.5 °C.

Description of key information

Under the conditions of the study the solubility of the test material in n-octanol was determined to be greater than 250 g/L of solution at 20.0 ± 0.5 °C.

Key value for chemical safety assessment

At the temperature of:
20 °C
Solubility in organic solvents at 20°C:
250 g/L

Additional information

The solubility in n-octanol of the test material was determined by a visual evaluation method, designed to be compatible with the CIPAC Handbook for the Analysis of Technical and Formulated Pesticides, Book H, Method MT 181. 

Under the conditions of the study the solubility of the test material in n-octanol was determined to be greater than 250 g/L of solution at 20.0 ± 0.5 °C.