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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Description of key information

Parent compound methyl chloroformate (CAS 79 -22 -1): Low bioaccumulation potential based on Log Kow < 3.

Hydrolysis product methanol (CAS 67 -56 -1): Low bioaccumulation potential based on Log Kow < 3.

Key value for chemical safety assessment

Additional information

In accordance with column 2 section 9.3.2 of REACH Annex IX, the study need not be conducted since the substance and its hydrolysis product have a log Kow less or equal than 3. Based on the log Pow of 0.14  (EPI Suite v4.11, 2019) calculated for methyl chloroformate bioaccumulation is not to be expected in aquatic organisms. However, the test substance rapidly hydrolyses and forms methanol which has an experimentally determined log Pow of -0.77 (Smith & Hansch, 2000) indicating that bioaccumulation of the hydrolysis product is not to be expected in aquatic organisms. In addition, a bioaccumulation study is not required under REACH for this tonnage band.

 

Therefore, and in terms of animal welfare, no further tests on bioaccumulation in fish are provided.