Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Conclusions for HXL-8366 are based on read across from analogue substances of a known category. See also Report 491517_Read-across approach for REACH registration of HXL-8366 , attached under 1. General information

Acute toxicity to fish (LL50) is > 100 mg/l, i.e. >> water solubility.

Acute toxicity to aquatic invertebrates (Daphnia) (EL50) is > 100 mg/l, i.e. >> water solubility.

Acute toxicity to aquatic plants (Algaer) (EL50) is > 100 mg/l, i.e. >> water solubility.

At a concentration of 100 mg/l, i.e. >> water solubility, the substances are not toxic to waste water (activated sludge) bacteria. 

 

 

EC #

Avg MW

Acute Toxicity to Fish (LL50)1

[mg/L]

Acute Toxicity to Aquatic Invertebrates (Daphnia) (EL50)1

[mg/L]

Toxicity to Aquatic Plants (algae) (EL50)1

[mg/L]

Respiration inhibition

(mg/L)

451-070-8

525

> 100 (>> ws)

> 100 (>> ws)

472(>> ws)

No inhibition

> 100

451-120-9

537

Read-across

Read-across

 > 100 (>> ws)

Read-across

451-190-0

544

Read-across

Read-across

Read-across

Read-across

453-150-8

554

2.6 E+03

(>> ws)

> 13 E+03

(>> ws)

> 13 E+03

(>> ws)

NOEC3-h> 13 E+03

(>> ws)

451-200-3

585

Read-across

Read-across

> 1002(>> ws)

Read-across

430-320-1

611

> 100 (>> ws)

> 100 (>> ws)

> 100 (>> ws)

IC503-h>1000

451-110-4

613

Read-across

Read-across

Read-across

Read-across

451-400-0

637

> 100 (>> ws)

> 100 (>> ws)

> 100 (>> ws)

IC5030-min>100

451-220-2

648

Read-across

Read-across

Read-across

Read-across

451-180-6

652

Read-across

Read-across

Read-across

Read-across

452-180-9

657

> 5 E+03

(>> ws)

Read-across

Read-across

Read-across

453-470-8

783

Read-across

Read-across

Read-across

Read-across

452-270-8

883

Read-across

Read-across

Read-across

Read-across

453-480-2

1012

> 100

> 100

> 100

IC5030-min>100

444-000-2

1023

> ws

> ws

> ws

IC503-h>1000

453-450-9

1036

Read-across

Read-across

Read-across

Read-across

453-490-7

1066

Read-across

Read-across

Read-across

Read-across

453-460-3

1094

Read-across

Read-across

 

Read-across

HXL-8366 (700 -325 -4)

878

Read-across: > ws

Read-across:

> ws

Read-across:

> ws

Read-across:

> 100

1Based on loading rate (LL /EL= Lethal dose/Effect level of Loading rate); WAF method used with filtration

2value = ELr50