Registration Dossier

Administrative data

Description of key information

Conclusions for HXL-8366 are based on read across from analogue substances of a known category. See also Report 491517_Read-across approach for REACH registration of HXL-8366 , attached under 1. General information

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
2 000 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Dose descriptor:
LC50
5.33 mg/m³

Acute toxicity: via dermal route

Endpoint conclusion
Dose descriptor:
LD50
2 000 mg/kg bw

Additional information

 

 

EC #

Avg MW

Acute oral

[mg/kg]

Acute dermal

[mg/kg]

Acute inhalation

[mg/L air]

451-070-8

525

> 2000

> 2000

Read-across

451-120-9

537

> 2000

> 2000

Read-across

451-190-0

544

Read-across

Read-across

Read-across

453-150-8

554

> 2000

Read-across

> 5.33 mg/L

451-200-3

585

Read-across

Read-across

Read-across

430-320-1

611

> 5000

> 2000

Read-across

451-110-4

613

Read-across

Read-across

Read-across

451-400-0

637

> 2000

> 2000

Read-across

451-220-2

648

Read-across

Read-across

Read-across

451-180-6

652

Read-across

Read-across

Read-across

452-180-9

657

> 2000

Read-across

> 6.48 mg/L

453-470-8

783

> 2000

Read-across

Read-across

452-270-8

883

> 2000

Read-across

Read-across

453-480-2

1012

> 2000

> 2000

Read-across

444-000-2

1023

> 2000

> 2000

Read-across

453-450-9

1036

Read-across

Read-across

Read-across

453-490-7

1066

Read-across

Read-across

Read-across

453-460-3

1094

Read-across

Read-across

Read-across

HXL-8366 (700 -325 -4)

878

Read-across:

> 2000

Read-across:

> 2000

Read-across:

> 5.33

Justification for classification or non-classification

Based on the information above mentioned 'discussion' the substance is not classified for acute toxicity.