Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

Conclusions for HXL-8366 are based on read across from analogue substances of a known category. See also Report 491517_Read-across approach for REACH registration of HXL-8366 , attached under 1. General information

Information on the environmental fate and pathways of the members of the category, including HXL-833 (700 -325 -4), is summarized in the table below. Since the members of the category have similar physico-chemical propererties, their behaviour in the envirnoment is also similar. Therefore, the category approach is justified.

 

 

EC #

Avg MW

Biodegradation (% in 28 days)

Hydrolysis

Adsorption/desorption coefficient

(log Koc, estimated)

451-070-8

525

not ready (64%)

Not measurable

≥ 4.3 (QSAR)

451-120-9

537

Read-across

Not measurable

Read-across

451-190-0

544

Read-across

Read-across

Read-across

453-150-8

554

2

Read-across

Read-across

451-200-3

585

Read-across

Read-across

Read-across

430-320-1

611

not ready (62%)

Not measurable

> 5.63 (QSAR)

451-110-4

613

Read-across

Read-across

≥ 4.4 (QSAR)

451-400-0

637

not ready (20%)

Not measurable

≥ 4.3

451-220-2

648

Read-across

Read-across

Read-across

451-180-6

652

Read-across

Read-across

Read-across

452-180-9

657

not ready (5.2%)

Read-across

Read-across

453-470-8

783

Read-across

Read-across

≥ 5.8 (QSAR)

452-270-8

883

Read-across

Read-across

≥ 5.8 (QSAR)

453-480-2

1012

not ready (79%)1

Read-across

≥ 5.7 (QSAR)

444-000-2

1023

not ready (14%)

Read-across

> 5.63

453-450-9

1036

Read-across

Read-across

≥ 6.4 (QSAR)

453-490-7

1066

Read-across

Read-across

≥ 6.6 (QSAR)

453-460-3

1094

Read-across

Read-across

≥ 5.8 (QSAR)

700-325-4

878

Read-across:

Not ready

Read-across:

Not measurable

Read-across:

≥ 4.3

 

1Not within 10-day window.

2Inherent biodegradability test, result: inherently biodegradable

Avg MW = Average molecular weight