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Based on Read-Across with 2,2-Bis(chloromethyl)trimethylene bis[bis(2-chloroethyl)phophate


Table 6.3.1 Summary of the terrestrial toxicity test results


 












































































Test species



Test protocol



Year test completed



Endpoint and exposure period



Result (mg/kg)



Reliability assessment



Comments



Reference



Toxicity to earthworm



 



 



 



 



 



 



 



Earthworms (Eisenia foetida)



OECD 207 (Limit test)



1996



14-day NOEC (mg/kg dry weight)


14-day LC50(mg/kg dry weight)



>1000


 


   
>1000



(2) valid with restrictions



The test was not subject to GLP. The test is of an overall acceptable standard



Wetton PM & Handley JW, 1996



Toxicity to higher plants



 



 



 



 



 



 



 



Wheat (Triticum aestivum), Mustard (Sinapsis alba), Lettuce (Lactuca sativa) (TCPP)



OECD Guideline 208



2003



NOEC (growth):


Wheat


Mustard


Lettuce


 


NOEC (seedling emergence):


Wheat


Mustard


Lettuce


(mg/kg dw)



 


22


29


18


 


 


>98


30


17



(1) valid without restriction



Study conducted using a similar test substance (TCPP)


Fulfils all reliability criteria. A fully valid GLP study


 



Servajean E, 2003



Toxicity to soil micro-organisms



 



 



 



 



 



 



 



Nitrifying micro-organisms in sandy loam soil (TDCP)



OECD Guideline 216



2005



NOEC (micro-organism activity based on nitrate concentration); 28 days


(mg/kg soil)



128



(1) valid without restriction



Study conducted using a similar test substance (TDCP)


Fulfils all the reliability criteria. The study was subject to GLP



van Ginkel CG, 2005