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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

Key value for chemical safety assessment

LC50 for freshwater fish:
52 mg/L

Additional information

Based on Read-Across with 2,2-Bis(chloromethyl)trimethylene bis[bis(2-chloroethyl)phophate


Test data


Two acute toxicity tests have been carried out with the fish species Oncorhynchus mykiss (Rainbow trout).


One of the tests (L'Haridon, 2002) was conducted over a range of test concentrations, was supported by analysis of exposure concentrations and was subject to GLP. The test gave a 96-hour LC50value of 52 mg/l. This result provides a suitable basis for deriving a PNECwater.


 


QSAR's


Estimated values of 32 and 17 mg/l have been derived for acute (96-hour LC50) fish toxicity using ECOSAR QSARs applicable to esters and phosphate esters respectively. The values are consistent with those obtained in the reported studies.


 


Reference:


European Union Risk Assessment Report "2,2-Bis(chloromethyl)trimethylene bis[bis(2-chloroethyl)phophate]" (V6), CAS 38051-10-4, May 2008