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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Publication from 1954, reporting only outcome of the study;no sufficient informations on test system/test method/evaluation method are given.

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
1954

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 401 (Acute Oral Toxicity)
GLP compliance:
not specified
Test type:
other: no data

Test material

Constituent 1
Chemical structure
Reference substance name:
Bis(2-butoxyethyl) ether
EC Number:
204-001-9
EC Name:
Bis(2-butoxyethyl) ether
Cas Number:
112-73-2
Molecular formula:
C12H26O3
IUPAC Name:
1-[2-(2-butoxyethoxy)ethoxy]butane

Test animals

Species:
rat
Strain:
Wistar
Sex:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
3 900 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
LD50 of DEGDBE in rats is reported as 3900 mg/kg bw. No classification is warranted.
Executive summary:

According to Smyth et al. 1954 the LD50 for DEGDBE is reported to be 3900 mg/kg bw for rats.