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EC number: 204-001-9 | CAS number: 112-73-2
DEGDBE is of low acute oral and dermal toxicity.
On the basis of the test results given below and in conformity with the criteria given in Annex VI to Commission Directive 2001/59/EC as well as inAnnex I of Regulation (EC) 1272/2008, the substance should be not classified
On the basis of the test results given below and in conformity with the criteria given in inOECD-GHS (Globally Harmonized System of Classification and Labelling of Chemicals), the substance should be classified into category 5.
LD50: > 2000 mg /kg bw
Species/strain: WISTAR Crl: WI(Han) rats
Vehicle (moistening): no vehicle used
Number of animals: 5 male and 5 female
Duration of exposure: 24 hours
Numberof Intercurrent Deaths
Signs of toxicity related to dose level used, time of onset and duration:
No treatment-related effects were observed.
Effect on organs (related to dose level):
No valid acute oral toxicity study is available for DEGDBE. However one secondary source, reporting 3900 mg/kg bw as LD50 for rats and one 8 -day repeated dose toxicity study in pregnant mice in which the LD10 is given as 2000 mg/kg bw. These informations are clearly demonstrating low acute oral toxicity.
The acute dermal toxicity was investigated according to the OECD Guideline 402. At dose level of 2000 mg/kg bw no mortality and no indiciation of toxicity was found.
For the exposure routes oral and dermal, low toxicity potential after single application could be obviously demonstrated based on the available data. No classification is warranted for the endpoint acute oral and acute dermal toxicity. No data is available for the inhalation route.
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