Registration Dossier
Registration Dossier
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EC number: 201-961-0 | CAS number: 90-02-8
Eye irritation
Administrative data
- Endpoint:
- eye irritation
- Remarks:
- other: read across from analogy
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: The target chemical should be classified as Aldehyde AND Aryl by Organic Functional groups (extended)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
Materials and methods
Test guideline
- Guideline:
- other: read-across by QSAR toolbox
- GLP compliance:
- no
Test material
- Reference substance name:
- Salicylaldehyde
- EC Number:
- 201-961-0
- EC Name:
- Salicylaldehyde
- Cas Number:
- 90-02-8
- Molecular formula:
- C7H6O2
- IUPAC Name:
- 2-hydroxybenzaldehyde
- Reference substance name:
- 4-(methylthio)benzaldehyde
- EC Number:
- 222-365-7
- EC Name:
- 4-(methylthio)benzaldehyde
- Cas Number:
- 3446-89-7
- IUPAC Name:
- 4-(methylsulfanyl)benzaldehyde
- Reference substance name:
- 4-formylbenzoic acid
- EC Number:
- 210-607-4
- EC Name:
- 4-formylbenzoic acid
- Cas Number:
- 619-66-9
- IUPAC Name:
- 4-formylbenzoic acid
- Details on test material:
- CAS number:3446-89-7
Chemical name(s):4-(methylsulfanyl)benzaldehyde
CAS number: 619-66-9
Chemical name(s): 4-formylbenzoic acid
Constituent 1
Constituent 2
Constituent 3
Test animals / tissue source
- Species:
- rabbit
Results and discussion
In vivo
Results
- Irritation parameter:
- other: MMAS
- Time point:
- other: 3d
- Score:
- ca. 25
- Reversibility:
- not specified
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
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