Registration Dossier

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Valid acute studies based on international guidelines are available for the three aquatic trophic levels (algae, aquatic invertebrates and fish). Among all data available, a toxic effect was observed for the three aquatic trophic levels:


- For the algae Pseudokirchneriella subcapitata, the 72h-ErC50 and 72h-NOEC values based on growth rate were determined to be 4.8 mg/L and 0.55 mg/L, respectively, based on geometric mean measured concentrations. 


- For the aquatic invertebrates Daphnia magna, the 48h-EC50 value was determined to be 2.6 mg/L based on geometric mean concentrations.


- The fish, Pimephales promelas, is the most sensitive species with a 96h-LC50 value at 2.3 mg/L based on measured concentration.


In addition, the test item was toxic to activated sludge of a municipal sewage treatment plan with 3h-EC50 and 3h-EC10 values determined to be 52 mg/L and 9.3 mg/L, respectively, based on nominal concentrations. 


 

Additional information

This dossier is a partial opt-out dossier including only endpoints of Annex VIII (Acute toxicity to fish and toxicity to microorganisms).


Annex VII endpoints (acute toxicity to aquatic invertebrates and toxicity to aquatic algae) are available in the dossier of the lead registrant.