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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Description of key information

Calculation with ECOSAR v1.00 (EPIWIN software by US-EPA): LC50(96h): 89.87 mg/L

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
89.87 mg/L

Additional information

The acute toxicity to daphnids of the test substance was predicted by the computer program ECOSAR v1.00 (EPIWIN software) by US-EPA (Chemservice GmbH, 2011). An extensive set of structure – activity relationships (SARs) is utilized by the computer program, to predict the acute and chronic toxicity for three trophic levels for aquatic species, based on the Vinyl / Allyl Ketones.The mode of toxic action for most neutral organic chemicals is narcosis, and many chemical classes present toxicity to organisms via narcosis (i.e. ethers, alcohols, ketones). However, some organic chemical classes have been identified as having a more specific mode of toxicity. These are typically organics that are reactive and ionizable and that exhibit excess toxicity in addition to narcosis (i.e. acrylates, epoxides, anilines). For Daphnia an LC50 of 89.87 mg/L is predicted (exposure period 48 h).