Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
1.01 µg/L
Assessment factor:
10
PNEC freshwater (intermittent releases):
5.53 µg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0.101 µg/L
Assessment factor:
100
PNEC marine water (intermittent releases):
0.553 µg/L

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
3.83 mg/L
Assessment factor:
100

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
22.26 µg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
2.226 µg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
3.848 µg/kg soil dw

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

Conclusion on classification

The following available data on the test item has been used to conclude on the classification for aquatic toxicity:


 


Fish


Short-term


Japanese guideline study (GLP), Oryzias latipes (Himedaka), 96 h, semi-static, LC50 (96h) = 5.7 mg/L (time-weighted mean)


EU Method C.1 (GLP), Danio rerio (Zebra fish), 96 h, semi-static, LC50 (96h) = 6.5 mg/L (geometric mean)


Long-term


OECD 210 (GLP), Danio rerio, 36 d, flow-through, NOEC = 0.0101 mg/L


 


Aquatic invertebrates


Short-term


Japanese guideline study (GLP), Daphnia magna, 48 h, static: EC50 (48h) = 15 mg/L (geometric mean)


Long-term


OECD 211 (GLP), Daphnia magna, 21 d, semi-static, NOEC >= 2.281 mg/L


 


Aquatic algae


Japanese guideline study (GLP), Pseudokirchneriella subcapitata, growth rate, ErC50 (72h) = 0.553 mg/L (initial mean), NOErC (72h) = 0.202 mg/L


 


Microorganisms


ISO8192 (OECD 209), EC50(3h) = 383 mg/L nominal 


 


Biodegradation


EU Method C.4-D, readily biodegradable


 


Based on the results of the available studies the most sensitive endpoint for chronic toxicity was determined to be the 36 d NOEC for the effect parameter hatchability with a value of 0.0101 mg test item/L (long-term study with the freshwater fish Danio rerio according to OECD 210 (Nierzedska, 2022)). The NOEC for the effect parameter post-hatch survival was determined to be 0.0358 mg/L and the NOEC for the effect parameters fresh-weight, dry-weight and length were determined to be higher than or equal to 0.623 mg/L, respectively. The most sensitive endpoint for acute aquatic toxicity was established as the ErC50 (72h) = 0.553 mg/L of the algae toxicity study.


 


With these findings the registered substance is classified as acutely hazardous to the aquatic environment Category 1; H400 "Very toxic to aquatic life" and chronic hazardous to the aquatic environment Category 2; H411 "Toxic to aquatic life with long lasting effects" according to Regulation (EC) No 1272/2008.