Registration Dossier

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
6.5 µg/L
Assessment factor:
1 000
Extrapolation method:
assessment factor
PNEC freshwater (intermittent releases):
65 µg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0.65 µg/L
Assessment factor:
10 000
Extrapolation method:
assessment factor

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
3.83 mg/L
Assessment factor:
100
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
143.26 µg/kg sediment dw
Extrapolation method:
sensitivity distribution

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
14.32 µg/kg sediment dw
Extrapolation method:
sensitivity distribution

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
28.29 µg/kg soil dw
Extrapolation method:
sensitivity distribution

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

PNECs

The PNECs for the different compartment have been calculated either by application an assessment factor (PNECfreshwater, PNECmarine water, PNECintermittent release and PNECstp) or using the equilibrium assumption method (PNECsediment freshwater, PNECsediment marine water and PNECsoil). The PNECoral is not considered as relevant due to lack of bioaccumulation potential. The utilized procedures are described in detail in the ECHA REACH Guidance of May 2008, Chapter R.10 ("Guidance on information requirements and chemical safety assessment").

Classification and Labelling

Most critical parameter was obtained by the conducted experiment with Danio rerio according to OECD 203 (Kanne, 1993). The LC50(96h) value of 6.5 mg/L indicates a potential of toxicity towards this freshwater species. However, since 4-phenylbutenone is readily biodegradable (81 % degradation after 28 d, Kanne, 1993) and the determined Bioconcentration Factor (BCF) of 10.8 (Chemservice S.A., 2011) as well as the obtained logPow (2.04, QSAR and several databases) indicate no potential to accumulate in biota, the substance has not to be classified and labelled according to Regulation (EC) No. 1272/2008 concerning environmental issues.

Conclusion on classification

Considering all available data of the acute and chronic toxicity tests on aquatic organisms, environmental fate issues and taking into account the provisions laid down in Council Directive 67/548/EEC and Regulation (EC) No. 1272 /2008, the substance does not need to be classified with respect to acute and long-term toxicity towards environmental organisms.