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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Link to relevant study record(s)

Description of key information

An OECD 211 (daphnia reproduction) guideline study on EC 283-392-8 was used for read-across. The 21 day IC50s for neonate production, adult daphnid length and adult daphnid weight were > 0.8 mg/L based on nominal loading rates and >0.53 mg/L based on measured concentrations. The NOECs were 0.4 mg/L nominal (0.26 mg/L measured) for reproduction and 0.8 mg/L nominal (0.53 measured) for both daphnid length and daphnid weight, the latter being the highest level tested. The LOECs were 0.8 mg/L nominal for reproduction and >0.8 mg/L nominal for daphnid length and weight.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
0.4 mg/L

Additional information

Read-across from other, structurally closely related ZDDPs is justified because of structural similarity and analogy of properties and effects. These are apparent from the physico-chemical properties, ecotoxicity, mammalian toxicity and fate, and supported by predictions using models.