Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

In a delayed contact hypersensitivity study in Guinea pigs (Buehler technique), 20 Hartley strain Guinea pigs were induced with 5% w/v test substance and then challenged with 1% w/v (Morris T.D., 1997). Irritation was noted in 3/20 animals following the 24 hour challenge phase. This irritation did not persist to 48 hours indicating an irritation response rather than a skin sensitization response. The test substance does not appear to be a sensitizer in the guinea pig.

Migrated from Short description of key information:
Read-across from an OECD 406 guideline study on EC 283-392-8. The test material is not a skin sensitizer.

Respiratory sensitisation

Endpoint conclusion
Additional information:
Migrated from Short description of key information:
No data available for respiratory sensitization.

Justification for classification or non-classification

In accordance to Directive 67/548/EEC and EU CLP (Regulation (EC) No. 1272/2008), this substance does not meet the criteriafor classification as a skin sensitizer.