Registration Dossier

Administrative data

Endpoint:
dissociation constant
Type of information:
other: handbook
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Reliable with restrictions; secondary literature source.

Data source

Reference
Reference Type:
review article or handbook
Title:
Dissociation Constants of Organic Bases in Aqueous Solution
Author:
Perrin DD
Year:
1972
Bibliographic source:
IUPAC Chem Data Ser: Suppl 1972 Buttersworth, London

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: No guideline available
Principles of method if other than guideline:
Unknown method, as provided in a reputable handbook. We defer to the editors of the Handbook to ensure that valid methods were used to generate this data. Handling experience with this value has not resulted in the questioning of its accuracy.
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent

Results and discussion

Dissociating properties:
not determined
Dissociation constant
No.:
#1
pKa:
1.39
Temp.:
24 °C
Remarks on result:
other: pKa = 1.39 @ 24°C

Applicant's summary and conclusion

Conclusions:
The dissociation constant of the substance 3-CyanoPyridine is pKa = 1.39 at 24°C.